Caldesmon anticorps (AA 1-240)
Aperçu rapide pour Caldesmon anticorps (AA 1-240) (ABIN6137866)
Antigène
Voir toutes Caldesmon (CALD1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-240
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Séquence
- MDDFERRREL RRQKREEMRL EAERIAYQRN DDDEEEAARE RRRRARQERL RQKQEEESLG QVTDQVEVNA QNSVPDEEAK TTTTNTQVEG DDEAAFLERL ARREERRQKR LQEALERQKE FDPTITDASL SLPSRRMQND TAENETTEKE EKSESRQERY EIEETETVTK SYQKNDWRDA EENKKEDKEK EEEEEEKPKR GSIGENQIKD EKIKKDKEPK EEVKSFMDRK KGFTEVKSQN
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Réactivité croisée
- Humain
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human CALD1 (NP_004333.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
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Autre désignation
- CALD1
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Sujet
- This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.,CALD1,CDM,H-CAD,HCAD,L-CAD,LCAD,NAG22,caldesmon,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Actins,Cardiovascular,Heart,Contractility,CALD1
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Poids moléculaire
- 61 kDa/62 kDa/64 kDa/65 kDa/93 kDa
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ID gène
- 800
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UniProt
- Q05682
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Pathways
- Myometrial Relaxation and Contraction
Antigène
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