Cadherin 4 anticorps (AA 757-916)

N° du produit ABIN6138295

L’anticorps Lapin Polyclonal anti-Cadherin 4 a été validé pour WB. Il convient pour détecter Cadherin 4 dans des échantillons de Humain.

Aperçu rapide pour Cadherin 4 anticorps (AA 757-916) (ABIN6138295)

Antigène: Cadherin 4 (CDH4)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin 4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Cadherin 4 anticorps

Épitope: AA 757-916

Séquence: KRREKERHTK QLLIDPEDDV RDNILKYDEE GGGEEDQDYD LSQLQQPEAM GHVPSKAPGV RRVDERPVGA EPQYPIRPMV PHPGDIGDFI NEGLRAADND PTAPPYDSLL VFDYEGSGST AGSVSSLNSS SSGDQDYDYL NDWGPRFKKL ADMYGGGEED

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 757-916 of human CDH4 (NP_001785.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Cadherin 4

Antigène: Cadherin 4 (CDH4)

Autre désignation: CDH4

Sujet: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.,CDH4,CAD4,R-CAD,RCAD,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cadherins,Cytoskeleton,Neuroscience,CDH4

Poids moléculaire: 92 kDa/100 kDa

ID gène: 1002

UniProt: P55283

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size