CLPS anticorps (C-Term)
Aperçu rapide pour CLPS anticorps (C-Term) (ABIN6138742)
Antigène
Voir toutes CLPS AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- ALGLARCTSM ASENSECSVK TLYGIYYKCP CERGLTCEGD KTIVGSITNT NFGICHDAGR SKQ
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Réactivité croisée
- Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthetic peptide corresponding to a sequence within amino acids 50 to the C-terminus of human CLPS (NP_001823.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- CLPS (Colipase, Pancreatic (CLPS))
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Autre désignation
- CLPS
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Sujet
- The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.,CLPS,colipase,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Lipases,Cardiovascular,Lipids,CLPS
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Poids moléculaire
- 11 kDa
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ID gène
- 1208
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UniProt
- P04118
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Pathways
- Lipid Metabolism
Antigène
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