COMT anticorps (AA 42-221)

N° du produit ABIN6138867

Cet anticorps Lapin Polyclonal détecte spécifiquement COMT dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour COMT anticorps (AA 42-221) (ABIN6138867)

Antigène: COMT (Catechol-O-Methyltransferase (COMT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COMT est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-COMT anticorps

Épitope: AA 42-221

Séquence: VGDKKGKIVD AVIQEHQPSV LLELGAYCGY SAVRMARLLS PGARLITIEI NPDCAAITQR MVDFAGVKDK VTLVVGASQD IIPQLKKKYD VDTLDMVFLD HWKDRYLPDT LLLEECGLLR KGTVLLADNV ICPGAPDFLA HVRGSSCFEC THYQSFLEYR EVVDGLEKAI YKGPGSEAGP

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 42-221 of human COMT (NP_009294.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur COMT

Antigène: COMT (Catechol-O-Methyltransferase (COMT))

Autre désignation: COMT

Sujet: Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.,COMT,HEL-S-98n,Epigenetics & Nuclear Signaling,Signal Transduction,Endocrine & Metabolism,Drug metabolism,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,COMT

Poids moléculaire: 24 kDa/30 kDa

ID gène: 1312

UniProt: P21964

Pathways: Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome