Cathepsin D anticorps (AA 65-412)

N° du produit ABIN6139223

Détail du produit anti-Cathepsin D anticorps

Antigène: Cathepsin D (CTSD)

Épitope: AA 65-412

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin D est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: GPIPEVLKNY MDAQYYGEIG IGTPPQCFTV VFDTGSSNLW VPSIHCKLLD IACWIHHKYN SDKSSTYVKN GTSFDIHYGS GSLSGYLSQD TVSVPCQSAS SASALGGVKV ERQVFGEATK QPGITFIAAK FDGILGMAYP RISVNNVLPV FDNLMQQKLV DQNIFSFYLS RDPDAQPGGE LMLGGTDSKY YKGSLSYLNV TRKAYWQVHL DQVEVASGLT LCKEGCEAIV DTGTSLMVGP VDEVRELQKA IGAVPLIQGE YMIPCEKVST LPAITLKLGG KGYKLSPEDY TLKVSQAGKT LCLSGFMGMD IPPPSGPLWI LGDVFIGRYY TVFDRDNNRV GFAEAARL

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 65-412 of human Cathepsin D (NP_001900.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Cathepsin D

Antigène: Cathepsin D (CTSD)

Autre désignation: CTSD (CTSD Produits)

Synonymes: anticorps catD, anticorps fb93e11, anticorps fj17b09, anticorps wu:fb93e11, anticorps wu:fj17b09, anticorps LOC398557, anticorps Cathd, anticorps CatD, anticorps LOC100136761, anticorps CTSD, anticorps DKFZp469J0315, anticorps DDBDRAFT_0205785, anticorps DDBDRAFT_0215012, anticorps DDB_0205785, anticorps DDB_0215012, anticorps CLN10, anticorps CPSD, anticorps CD, anticorps cathepsin D, anticorps cathepsin D S homeolog, anticorps lysosomal aspartic protease, anticorps cathepsin D-like, anticorps ctsd, anticorps LOC398557, anticorps ctsd.S, anticorps CatD, anticorps LOC5567565, anticorps LOC100136761, anticorps CTSD, anticorps Cathd, anticorps ctsD, anticorps catd, anticorps Ctsd, anticorps LOC443060

Sujet: This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.,CLN10,CPSD,HEL-S-130P,Cathepsin D,CTSD,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Extracellular Matrix,Ubiquitin,Neuroscience,CTSD

Poids moléculaire: 44 kDa

ID gène: 1509

UniProt: P07339

Pathways: Peptide Hormone Metabolism