DCPS anticorps (AA 1-270)

N° du produit ABIN6139449

Cet anticorps anti-DCPS est un anticorps Lapin Polyclonal détectant DCPS dans WB. Adapté pour Humain.

Aperçu rapide pour DCPS anticorps (AA 1-270) (ABIN6139449)

Antigène: DCPS (Decapping Enzyme, Scavenger (DCPS))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCPS est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DCPS anticorps

Épitope: AA 1-270

Séquence: MADAAPQLGK RKRELDVEEA HAASTEEKEA GVGNGTCAPV RLPFSGFRLQ KVLRESARDK IIFLHGKVNE ASGDGDGEDA VVILEKTPFQ VEQVAQLLTG SPELQLQFSN DIYSTYHLFP PRQLNDVKTT VVYPATEKHL QKYLRQDLRL IRETGDDYRN ITLPHLESQS LSIQWVYNIL DKKAEADRIV FENPDPSDGF VLIPDLKWNQ QQLDDLYLIA ICHRRGIRSL RDLTPEHLPL LRNILHQGQE AILQRYRMKG DHLRVYLHYL

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human DCPS (NP_054745.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DCPS

Antigène: DCPS (Decapping Enzyme, Scavenger (DCPS))

Autre désignation: DCPS

Sujet: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG with up to 10 nucleotide substrates (small capped oligoribonucleotides and specifically releases 5'-phosphorylated RNA fragments and 7-methylguanosine monophosphate (m7GMP. Cleaves cap analog structures like tri-methyl guanosine nucleoside triphosphate (m3(2,2,7GpppG with very poor efficiency. Does not hydrolyze unmethylated cap analog (GpppG and shows no decapping activity on intact m7GpppG-capped mRNA molecules longer than 25 nucleotides. Does not hydrolyze 7-methylguanosine diphosphate (m7GDP to m7GMP. May also play a role in the 5'->3 mRNA decay pathway, m7GDP, the downstream product released by the 5'->3' mRNA mediated decapping activity, may be also converted by DCPS to m7GMP. Binds to m7GpppG and strongly to m7GDP. Plays a role in first intron splicing of pre-mRNAs. Inhibits activation-induced cell death.,DCPS,ARS,DCS1,HINT-5,HINT5,HSL1,HSPC015,Epigenetics & Nuclear Signaling,DCPS

Poids moléculaire: 38 kDa

ID gène: 28960

UniProt: Q96C86