DUOX1 anticorps (AA 1312-1551)

N° du produit ABIN6139857

L’anticorps Lapin Polyclonal anti-DUOX1 a été validé pour WB. Il convient pour détecter DUOX1 dans des échantillons de Humain.

Aperçu rapide pour DUOX1 anticorps (AA 1312-1551) (ABIN6139857)

Antigène: DUOX1 (Dual Oxidase 1 (DUOX1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUOX1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DUOX1 anticorps

Épitope: AA 1312-1551

Séquence: ALGTTEYHPF TLTSAPHEDT LSLHIRAAGP WTTRLREIYS APTGDRCARY PKLYLDGPFG EGHQEWHKFE VSVLVGGGIG VTPFASILKD LVFKSSVSCQ VFCKKIYFIW VTRTQRQFEW LADIIREVEE NDHQDLVSVH IYITQLAEKF DLRTTMLYIC ERHFQKVLNR SLFTGLRSIT HFGRPPFEPF FNSLQEVHPQ VRKIGVFSCG PPGMTKNVEK ACQLINRQDR THFSHHYENF

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1312-1551 of human DUOX1 (NP_059130.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DUOX1

Antigène: DUOX1 (Dual Oxidase 1 (DUOX1))

Autre désignation: DUOX1

Sujet: The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.,DUOX1,LNOX1,NOXEF1,THOX1,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Neuroscience,DUOX1

Poids moléculaire: 137 kDa/177 kDa

ID gène: 53905

UniProt: Q9NRD9