DUSP12 anticorps (AA 130-270)

N° du produit ABIN6139861

Cet anticorps anti-DUSP12 est un anticorps Lapin Polyclonal détectant DUSP12 dans WB. Adapté pour Humain.

Aperçu rapide pour DUSP12 anticorps (AA 130-270) (ABIN6139861)

Antigène: DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP12 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DUSP12 anticorps

Épitope: AA 130-270

Séquence: LMKTDQLPFE KAYEKLQILK PEAKMNEGFE WQLKLYQAMG YEVDTSSAIY KQYRLQKVTE KYPELQNLPQ ELFAVDPTTV SQGLKDEVLY KCRKCRRSLF RSSSILDHRE GSGPIAFAHK RMTPSSMLTT GRQAQCTSYF I

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 130-270 of human DUSP12 (NP_009171.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DUSP12

Antigène: DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))

Autre désignation: DUSP12

Sujet: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain.,DUSP12,DUSP1,YVH1,Signal Transduction,DUSP12

Poids moléculaire: 37 kDa

ID gène: 11266

UniProt: Q9UNI6

Pathways: Regulation of Carbohydrate Metabolic Process