Fibrillarin anticorps (AA 100-321)

N° du produit ABIN6140494

L’anticorps Lapin Polyclonal anti-Fibrillarin a été validé pour WB, IP et IF. Il convient pour détecter Fibrillarin dans des échantillons de Humain.

Aperçu rapide pour Fibrillarin anticorps (AA 100-321) (ABIN6140494)

Antigène: Fibrillarin (FBL)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Fibrillarin est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Détail du produit anti-Fibrillarin anticorps

Épitope: AA 100-321

Séquence: RGKEDALVTK NLVPGESVYG EKRVSISEGD DKIEYRAWNP FRSKLAAAIL GGVDQIHIKP GAKVLYLGAA SGTTVSHVSD IVGPDGLVYA VEFSHRSGRD LINLAKKRTN IIPVIEDARH PHKYRMLIAM VDVIFADVAQ PDQTRIVALN AHTFLRNGGH FVISIKANCI DSTASAEAVF ASEVKKMQQE NMKPQEQLTL EPYERDHAVV VGVYRPPPKV KN

Réactivité croisée: Humain, Singe, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 100-321 of human Fibrillarin/U3 RNP (NP_001427.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:20 - 1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Fibrillarin

Antigène: Fibrillarin (FBL)

Autre désignation: FBL

Sujet: This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin.,FBL,FIB,FLRN,RNU3IP1,Nop1,Epigenetics & Nuclear Signaling,RNA Binding,FBL

Poids moléculaire: 33 kDa

ID gène: 2091

UniProt: P22087

Pathways: Ribonucleoside Biosynthetic Process