FLT3 anticorps (AA 650-750)

N° du produit ABIN6140691

Détail du produit anti-FLT3 anticorps

Antigène: FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

Épitope: AA 650-750

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FLT3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: ADSSEREALM SELKMMTQLG SHENIVNLLG ACTLSGPIYL IFEYCCYGDL LNYLRSKREK FHRTWTEIFK EHNFSFYPTF QSHPNSSMPG SREVQIHPDS D

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 650-750 of human FLT3 (NP_004110.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur FLT3

Antigène: FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

Autre désignation: FLT3 (FLT3 Produits)

Synonymes: anticorps FLT3, anticorps B230315G04, anticorps CD135, anticorps Flk-2, anticorps Flk2, anticorps Flt-3, anticorps Ly72, anticorps wmfl, anticorps FLK-2, anticorps FLK2, anticorps STK1, anticorps fms related tyrosine kinase 3, anticorps FMS-like tyrosine kinase 3, anticorps fms-related tyrosine kinase 3, anticorps FLT3, anticorps Flt3

Sujet: This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.,FLT3,CD135,FLK-2,FLK2,STK1,Signal Transduction,Kinase,Tyrosine kinases,Immunology & Inflammation,CD markers,Stem Cells,FLT3

Poids moléculaire: 108 kDa/112 kDa

ID gène: 2322

UniProt: P36888

Pathways: Signalisation RTK