GALE anticorps (AA 129-348)

N° du produit ABIN6140933

Cet anticorps anti-GALE est un anticorps Lapin Polyclonal détectant GALE dans WB et IHC. Adapté pour Humain.

Aperçu rapide pour GALE anticorps (AA 129-348) (ABIN6140933)

Antigène: GALE (UDP-Galactose-4-Epimerase (GALE))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GALE est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-GALE anticorps

Épitope: AA 129-348

Séquence: FSSSATVYGN PQYLPLDEAH PTGGCTNPYG KSKFFIEEMI RDLCQADKTW NAVLLRYFNP TGAHASGCIG EDPQGIPNNL MPYVSQVAIG RREALNVFGN DYDTEDGTGV RDYIHVVDLA KGHIAALRKL KEQCGCRIYN LGTGTGYSVL QMVQAMEKAS GKKIPYKVVA RREGDVAACY ANPSLAQEEL GWTAALGLDR MCEDLWRWQK QNPSGFGTQA

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 129-348 of human GALE (NP_001121093.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GALE

Antigène: GALE (UDP-Galactose-4-Epimerase (GALE))

Autre désignation: GALE

Sujet: This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified.,GALE,SDR1E1,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,GALE

Poids moléculaire: 30 kDa/38 kDa

ID gène: 2582

UniProt: Q14376

Pathways: Response to Water Deprivation, Cellular Glucan Metabolic Process