Metabotropic Glutamate Receptor 5 anticorps (AA 870-1070)

N° du produit ABIN6141427

L’anticorps Lapin Polyclonal anti-Metabotropic Glutamate Receptor 5 a été validé pour WB. Il convient pour détecter Metabotropic Glutamate Receptor 5 dans des échantillons de Humain.

Aperçu rapide pour Metabotropic Glutamate Receptor 5 anticorps (AA 870-1070) (ABIN6141427)

Antigène: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Metabotropic Glutamate Receptor 5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Metabotropic Glutamate Receptor 5 anticorps

Épitope: AA 870-1070

Séquence: GSSGETLRYK DRRLAQHKSE IECFTPKGSM GNGGRATMSS SNGKSVTWAQ NEKSSRGQHL WQRLSIHINK KENPNQTAVI KPFPKSTESR GLGAGAGAGG SAGGVGATGG AGCAGAGPGG PESPDAGPKA LYDVAEAEEH FPAPARPRSP SPISTLSHRA GSASRTDDDV PSLHSEPVAR SSSSQGSLME QISSVVTRFT A

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 870-1070 of human GRM5 (NP_001137303.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Metabotropic Glutamate Receptor 5

Antigène: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Autre désignation: GRM5

Sujet: This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.,GRM5,GPRC1E,MGLUR5,PPP1R86,mGlu5,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,Neurodegenerative Diseases,GRM5

Poids moléculaire: 105 kDa/128 kDa/132 kDa

ID gène: 2915

UniProt: P41594

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity