EPAS1 anticorps (AA 588-870)

N° du produit ABIN6141764

Cet anticorps Lapin Polyclonal détecte spécifiquement EPAS1 dans WB, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour EPAS1 anticorps (AA 588-870) (ABIN6141764)

Antigène: EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPAS1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-EPAS1 anticorps

Épitope: AA 588-870

Séquence: FQQQLESKKT EPEHRPMSSI FFDAGSKASL PPCCGQASTP LSSMGGRSNT QWPPDPPLHF GPTKWAVGDQ RTEFLGAAPL GPPVSPPHVS TFKTRSAKGF GARGPDVLSP AMVALSNKLK LKRQLEYEEQ AFQDLSGGDP PGGSTSHLMW KRMKNLRGGS CPLMPDKPLS ANVPNDKFTQ NPMRGLGHPL RHLPLPQPPS AISPGENSKS RFPPQCYATQ YQDYSLSSAH KVSGMASRLL GPSFESYLLP ELTRYDCEVN VPVLGSSTLL QGGDLLRALD QAT

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 588-870 of human EPAS1/HIF2alpha (NP_001421.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur EPAS1

Antigène: EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

Autre désignation: EPAS1

Sujet: This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.,EPAS1,ECYT4,HIF2A,HLF,MOP2,PASD2,bHLHe73,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Invasion and Metastasis,Endocrine & Metabolism,Nucleotide metabolism,Molecular processes,Cardiovascular,Angiogenesis,Hypoxia,HIF,EPAS1

Poids moléculaire: 96 kDa

ID gène: 2034

UniProt: Q99814

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2, L'effet Warburg