Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

HIRA anticorps (AA 250-550)

HIRA Reactivité: Humain WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6141776
  • Antigène Voir toutes HIRA Anticorps
    HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
    Épitope
    • 15
    • 8
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 250-550
    Reactivité
    • 43
    • 33
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 50
    • 10
    Lapin
    Clonalité
    • 50
    • 10
    Polyclonal
    Conjugué
    • 29
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HIRA est non-conjugé
    Application
    • 45
    • 23
    • 13
    • 13
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    AQIIEREGWK TNMDFVGHRK AVTVVKFNPK IFKKKQKNGS SAKPSCPYCC CAVGSKDRSL SVWLTCLKRP LVVIHELFDK SIMDISWTLN GLGILVCSMD GSVAFLDFSQ DELGDPLSEE EKSRIHQSTY GKSLAIMTEA QLSTAVIENP EMLKYQRRQQ QQQLDQKSAA TREMGSATSV AGVVNGESLE DIRKNLLKKQ VETRTADGRR RITPLCIAQL DTGDFSTAFF NSIPLSGSLA GTMLSSHSSP QLLPLDSSTP NSFGASKPCT EPVVAASARP AGDSVNKDSM NATSTPAALS P
     Réactivité croisée
    Humain
    Attributs du produit
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogène
    Recombinant fusion protein containing a sequence corresponding to amino acids 250-550 of human HIRA (NP_003316.3).
    Isotype
    IgG
  • Indications d'application
    WB,1:500 - 1:2000,IHC,1:100 - 1:200
    Commentaires

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
    Autre désignation
    HIRA (HIRA Produits)
    Synonymes
    anticorps HIRA, anticorps wu:fb97b07, anticorps wu:fi43b08, anticorps si:ch211-188g24.3, anticorps AA138857, anticorps D16Ertd95e, anticorps N28177, anticorps Tuple1, anticorps DGCR1, anticorps TUP1, anticorps TUPLE1, anticorps dgcr1, anticorps hira-A, anticorps tup1, anticorps tuple1, anticorps homolog of histone chaperone HIRA, anticorps histone cell cycle regulator, anticorps histone cell cycle regulator a, anticorps protein HIRA, anticorps HIR histone cell cycle regulation defective homolog A (S. cerevisiae), anticorps HIRA, anticorps histone cell cycle regulator S homeolog, anticorps histone chaperone HIRA-like protein, anticorps Tuple1/HirA, anticorps HIRA, anticorps hira, anticorps LOC100052845, anticorps LOC100352472, anticorps LOC100407742, anticorps LOC100450459, anticorps LOC100467668, anticorps LOC100581135, anticorps LOC486424, anticorps Hira, anticorps LOC732736, anticorps hira.S
    Sujet
    This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.,HIRA,DGCR1,TUP1,TUPLE1,Epigenetics & Nuclear Signaling,Chromatin Remodeling,Cell Biology & Developmental Biology,Stem Cells,Germline Stem Cells,HIRA
    Poids moléculaire
    89 kDa/111 kDa
    ID gène
    7290
    UniProt
    P54198
    Pathways
    Chromatin Binding
Vous êtes ici:
Support technique