HIRA anticorps

N° du produit ABIN7264499

Détail du produit anti-HIRA anticorps

Antigène: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIRA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human HIRA (NP_003316.3).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:100-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur HIRA

Antigène: HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))

Autre désignation: HIRA (HIRA Produits)

Synonymes: anticorps HIRA, anticorps wu:fb97b07, anticorps wu:fi43b08, anticorps si:ch211-188g24.3, anticorps AA138857, anticorps D16Ertd95e, anticorps N28177, anticorps Tuple1, anticorps DGCR1, anticorps TUP1, anticorps TUPLE1, anticorps dgcr1, anticorps hira-A, anticorps tup1, anticorps tuple1, anticorps homolog of histone chaperone HIRA, anticorps histone cell cycle regulator, anticorps histone cell cycle regulator a, anticorps protein HIRA, anticorps HIR histone cell cycle regulation defective homolog A (S. cerevisiae), anticorps HIRA, anticorps histone cell cycle regulator S homeolog, anticorps histone chaperone HIRA-like protein, anticorps Tuple1/HirA, anticorps HIRA, anticorps hira, anticorps LOC100052845, anticorps LOC100352472, anticorps LOC100407742, anticorps LOC100450459, anticorps LOC100467668, anticorps LOC100581135, anticorps LOC486424, anticorps Hira, anticorps LOC732736, anticorps hira.S

Sujet: This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.

Poids moléculaire:

Observed_MW: 112 kDa

Calculated_MW: 89 kDa/111 kDa

ID gène: 7290

UniProt: P54198

Pathways: Chromatin Binding