IL5RA anticorps (AA 20-335)
Aperçu rapide pour IL5RA anticorps (AA 20-335) (ABIN6142402)
Antigène
Voir toutes IL5RA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 20-335
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Séquence
- ADLLPDEKIS LLPPVNFTIK VTGLAQVLLQ WKPNPDQEQR NVNLEYQVKI NAPKEDDYET RITESKCVTI LHKGFSASVR TILQNDHSLL ASSWASAELH APPGSPGTSI VNLTCTTNTT EDNYSRLRSY QVSLHCTWLV GTDAPEDTQY FLYYRYGSWT EECQEYSKDT LGRNIACWFP RTFILSKGRD WLAVLVNGSS KHSAIRPFDQ LFALHAIDQI NPPLNVTAEI EGTRLSIQWE KPVSAFPIHC FDYEVKIHNT RNGYLQIEKL MTNAFISIID DLSKYDVQVR AAVSSMCREA GLWSEWSQPI YVGFSR
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 20-335 of human IL5RA (NP_783855.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
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Autre désignation
- IL5RA
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Sujet
- The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.,IL5RA,CD125,CDw125,HSIL5R3,IL5R,Immunology & Inflammation,CD markers,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,IL5RA
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Poids moléculaire
- 23 kDa/37 kDa/42 kDa/47 kDa
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ID gène
- 3568
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UniProt
- Q01344
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Pathways
- Signalistation JAK/STAT
Antigène
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