PHF17 anticorps (AA 210-509)
Aperçu rapide pour PHF17 anticorps (AA 210-509) (ABIN6142629)
Antigène
Voir toutes PHF17 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 210-509
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Séquence
- QSPDGEDGNE MVFCDKCNIC VHQACYGILK VPEGSWLCRT CALGVQPKCL LCPKKGGAMK PTRSGTKWVH VSCALWIPEV SIGSPEKMEP ITKVSHIPSS RWALVCSLCN EKFGASIQCS VKNCRTAFHV TCAFDRGLEM KTILAENDEV KFKSYCPKHS SHRKPEESLG KGAAQENGAP ECSPRNPLEP FASLEQNREE AHRVSVRKQK LQQLEDEFYT FVNLLDVARA LRLPEEVVDF LYQYWKLKRK VNFNKPLITP KKDEEDNLAK REQDVLFRRL QLFTHLRQDL ERVMIDTDTL
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 210-509 of human JADE1 (NP_079176.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IF,1:10 - 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- PHF17 (PHD Finger Protein 17 (PHF17))
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Autre désignation
- JADE1
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Sujet
- Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity. Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H4 acetylation (H4K5ac, H4K8ac and H4K12ac, regulating DNA replication initiation, regulating DNA replication initiation. May also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. Negatively regulates canonical Wnt signaling, at least in part, cooperates with NPHP4 in this function.,JADE1,PHF17,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,JADE1
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Poids moléculaire
- 58 kDa/94 kDa/95 kDa
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ID gène
- 79960
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UniProt
- Q6IE81
Antigène
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