JARID2 anticorps (AA 1027-1246)

N° du produit ABIN6142653

Cet anticorps Lapin Polyclonal détecte spécifiquement JARID2 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour JARID2 anticorps (AA 1027-1246) (ABIN6142653)

Antigène: JARID2 (Jumonji, AT Rich Interactive Domain 2 (JARID2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JARID2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-JARID2 anticorps

Épitope: AA 1027-1246

Séquence: ETVHFATTQW TSMGFETAKE MKRRHIAKPF SMEKLLYQIA QAEAKKENGP TLSTISALLD ELRDTELRQR RQLFEAGLHS SARYGSHDGS STVADGKKKP RKWLQLETSE RRCQICQHLC YLSMVVQENE NVVFCLECAL RHVEKQKSCR GLKLMYRYDE EQIISLVNQI CGKVSGKNGS IENCLSKPTP KRGPRKRATV DVPPSRLSAS SSSKSASSSS

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1027-1246 of human JARID2 (NP_004964.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur JARID2

Antigène: JARID2 (Jumonji, AT Rich Interactive Domain 2 (JARID2))

Autre désignation: JARID2

Sujet: This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies.,JARID2,JMJ,Epigenetics & Nuclear Signaling,Neuroscience,JARID2

Poids moléculaire: 106 kDa/119 kDa/138 kDa

ID gène: 3720

UniProt: Q92833

Pathways: Chromatin Binding