KIF14 anticorps (AA 1399-1648)
Aperçu rapide pour KIF14 anticorps (AA 1399-1648) (ABIN6142854)
Antigène
Voir toutes KIF14 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 1399-1648
-
Séquence
- LENGNNKAAS VQEEFMDAVC DGVGLGMKIL LDSGLEKAKE LQHELFRQCT KNEVTKEMKT NAMGLIRSLE NIFAESKIKS FRRQVQEENF EYQDFKRMVN RAPEFLKLKH CLEKAIEIII SALKGCHSDI NLLQTCVESI RNLASDFYSD FSVPSTSVGS YESRVTHIVH QELESLAKSL LFCFESEESP DLLKPWETYN QNTKEEHQQS KSSGIDGSKN KGVPKRVYEL HGSSPAVSSE ECTPSRIQWV
-
Réactivité croisée
- Humain, Souris, Rat
-
Attributs du produit
- Polyclonal Antibodies
-
Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1399-1648 of human KIF14 (NP_055690.1).
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB,1:1000 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
-
Commentaires
-
HIGH QUALITY
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- KIF14 (Kinesin Family Member 14 (KIF14))
-
Autre désignation
- KIF14
-
Sujet
- This gene encodes a member of the kinesin-3 superfamily of microtubule motor proteins. These proteins are involved in numerous processes including vesicle transport, chromosome segregation, mitotic spindle formation, and cytokinesis. In human HeLa-S3 and 293T cells, this protein is localized to the cytoplasm during interphase, to the spindle poles and spindle microtubules during mitosis, and to the midbody during cytokinesis. An internal motor domain displays microtubule-dependent ATPase activity, consistent with its function as a microtubule motor protein. Knockdown of this gene results in failed cytokinesis with endoreplication, which results in multinucleated cells. This gene has been identified as a likely oncogene in breast, lung and ovarian cancers, as well as retinoblastomas and gliomas. Alternative splicing results in multiple transcript variants.,KIF14,MKS12,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,Motor Proteins,KIF14
-
Poids moléculaire
- 186 kDa
-
ID gène
- 9928
-
UniProt
- Q15058
Antigène
-