MECOM anticorps (AA 1-120)

N° du produit ABIN6143677

Cet anticorps anti-MECOM est un anticorps Lapin Polyclonal détectant MECOM dans WB. Adapté pour Humain.

Aperçu rapide pour MECOM anticorps (AA 1-120) (ABIN6143677)

Antigène: MECOM (MDS1 and EVI1 Complex Locus (MECOM))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MECOM est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MECOM anticorps

Épitope: AA 1-120

Séquence: MRSKGRARKL ATNNECVYGN YPEIPLEEMP DADGVASTPS LNIQEPCSPA TSSEAFTPKE GSPYKAPIYI PDDIPIPAEF ELRESNMPGA GLGIWTKRKI EVGEKFGPYV GEQRSNLKDP

Réactivité croisée: Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human MECOM (NP_004982.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MECOM

Antigène: MECOM (MDS1 and EVI1 Complex Locus (MECOM))

Autre désignation: MECOM

Sujet: The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.,MECOM,AML1-EVI-1,EVI1,KMT8E,MDS1,MDS1-EVI1,PRDM3,RUSAT2,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,MECOM

Poids moléculaire: 18 kDa/117 kDa/118 kDa/125 kDa/139 kDa

ID gène: 2122

UniProt: Q03112, Q13465