TNNI1 anticorps

N° du produit ABIN614371

Détail du produit anti-TNNI1 anticorps

Antigène: TNNI1 (Slow Skeletal Troponin I (TNNI1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TNNI1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Recognizes Troponin I Skeletal (TNNI). Less than 0.05 % cross-reactivity with Cardiac TNI

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Protein A Chromatography.

Immunogène: Mouse Skeletal muscle Troponin I.

Clone: 12F10

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS, pH 7.4 with 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur TNNI1

Antigène: TNNI1 (Slow Skeletal Troponin I (TNNI1))

Abstract: TNNI1 Produits

Synonymes: anticorps ANM, anticorps NEM5, anticorps STNT, anticorps TNT, anticorps TNTS, anticorps TnI-S4, anticorps SSTNI, anticorps TNN1, anticorps 2700018B22Rik, anticorps AI747285, anticorps ssTnI, anticorps AW146156, anticorps Tnt, anticorps sTnT, anticorps ssTnT, anticorps Fang2, anticorps tnTs, anticorps troponin 1, anticorps zgc:86895, anticorps troponin T1, slow skeletal type, anticorps troponin I1, slow skeletal type, anticorps troponin I, skeletal, slow 1, anticorps troponin T1, skeletal, slow, anticorps troponin I1, slow skeletal type S homeolog, anticorps troponin I type 1 (skeletal, slow), anticorps troponin I4b, tandem duplicate 2, anticorps TNNT1, anticorps TNNI1, anticorps Tnni1, anticorps Tnnt1, anticorps tnni1.S, anticorps tnni4b.2

Sujet: Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium. This antibody reacts with subunit I of the troponin complex in human myocardium, where it is the only troponin I isotype present. It does not cross-react with troponin I of skeletal muscle cells.Synonyms: TNNI1

ID gène: 7135

NCBI Accession: NP_003272

UniProt: P19237