METAP2 anticorps (AA 1-220)

N° du produit ABIN6143752

Cet anticorps Lapin Polyclonal détecte spécifiquement METAP2 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour METAP2 anticorps (AA 1-220) (ABIN6143752)

Antigène: METAP2 (Methionyl Aminopeptidase 2 (METAP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp METAP2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-METAP2 anticorps

Épitope: AA 1-220

Séquence: MAGVEEVAAS GSHLNGDLDP DDREEGAAST AEEAAKKKRR KKKKSKGPSA AGEQEPDKES GASVDEVARQ LERSALEDKE RDEDDEDGDG DGDGATGKKK KKKKKKRGPK VQTDPPSVPI CDLYPNGVFP KGQECEYPPT QDGRTAAWRT TSEEKKALDQ ASEEIWNDFR EAAEAHRQVR KYVMSWIKPG MTMIEICEKL EDCSRKLIKE NGLNAGLAFP

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human METAP2 (NP_006829.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur METAP2

Antigène: METAP2 (Methionyl Aminopeptidase 2 (METAP2))

Autre désignation: METAP2

Sujet: The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene.,METAP2,MAP2,MNPEP,p67eIF2,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,METAP2

Poids moléculaire: 50 kDa/52 kDa

ID gène: 10988

UniProt: P50579

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling