MFN2 anticorps (AA 500-600)
Aperçu rapide pour MFN2 anticorps (AA 500-600) (ABIN6143800)
Antigène
Voir toutes MFN2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 500-600
-
Séquence
- GLKPLLPVSV RSQIDMLVPR QCFSLNYDLN CDKLCADFQE DIEFHFSLGW TMLVNRFLGP KNSRRALMGY NDQVQRPIPL TPANPSMPPL PQGSLTQEEF M
-
Réactivité croisée
- Humain, Souris, Rat
-
Attributs du produit
- Polyclonal Antibodies
-
Immunogène
- A synthetic peptide corresponding to a sequence within amino acids 500-600 of human Mitofusin 2 (NP_001121132.1).
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- MFN2 (Mitofusin 2 (MFN2))
-
Autre désignation
- MFN2
-
Sujet
- This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.,CMT2A,CMT2A2,CMT2A2A,CMT2A2B,CPRP1,HMSN6A,HSG,MARF,MFN2,Mitofusin 2,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Mitophagy fission and fusion,Neuroscience,Neurodegenerative Diseases,Mitochondrial Control of Autophagy,MFN2
-
Poids moléculaire
- 50 kDa/86 kDa
-
ID gène
- 9927
-
UniProt
- O95140
-
Pathways
- Skeletal Muscle Fiber Development
Antigène
-