SMCR7L anticorps (AA 40-280)

N° du produit ABIN6143839

L’anticorps anti-SMCR7L Polyclonal Lapin est utilisé pour la détection de SMCR7L dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour SMCR7L anticorps (AA 40-280) (ABIN6143839)

Antigène: SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMCR7L est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SMCR7L anticorps

Épitope: AA 40-280

Séquence: GIATLAVKRM YDRAISAPTS PTRLSHSGKR SWEEPNWMGS PRLLNRDMKT GLSRSLQTLP TDSSTFDTDT FCPPRPKPVA RKGQVDLKKS RLRMSLQEKL LTYYRNRAAI PAGEQARAKQ AAVDICAELR SFLRAKLPDM PLRDMYLSGS LYDDLQVVTA DHIQLIVPLV LEQNLWSCIP GEDTIMNVPG FFLVRRENPE YFPRGSSYWD RCVVGGYLSP KTVADTFEKV VAGSINWPAI G

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 40-280 of human MIEF1 (NP_061881.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SMCR7L

Antigène: SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))

Autre désignation: MIEF1

Sujet: Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L.,MIEF1,HSU79252,MID51,SMCR7L,dJ1104E15.3,Cell Biology & Developmental Biology,MIEF1

Poids moléculaire: 8 kDa/15 kDa/51 kDa

ID gène: 54471

UniProt: Q9NQG6