MXI1 anticorps (AA 170-295)

N° du produit ABIN6144206

L’anticorps Lapin Polyclonal anti-MXI1 a été validé pour WB. Il convient pour détecter MXI1 dans des échantillons de Humain.

Aperçu rapide pour MXI1 anticorps (AA 170-295) (ABIN6144206)

Antigène: MXI1 (MAX Interactor 1 (MXI1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MXI1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MXI1 anticorps

Épitope: AA 170-295

Séquence: HTTLGLLNKA KAHIKKLEEA ERKSQHQLEN LEREQRFLKW RLEQLQGPQE MERIRMDSIG STISSDRSDS EREEIEVDVE STEFSHGEVD NISTTSISDI DDHSSLPSIG SDEGYSSASV KLSFTS

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 170-295 of human MXI1 (NP_569157.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MXI1

Antigène: MXI1 (MAX Interactor 1 (MXI1))

Autre désignation: MXI1

Sujet: Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.,MXI1,MAD2,MXD2,MXI,bHLHc11,Epigenetics & Nuclear Signaling,Transcription Factors,MXI1

Poids moléculaire: 20 kDa/21 kDa/26 kDa/32 kDa

ID gène: 4601

UniProt: P50539

Pathways: Maintenance of Protein Location