MXI1 anticorps (AA 76-295)
Aperçu rapide pour MXI1 anticorps (AA 76-295) (ABIN6144207)
Antigène
Voir toutes MXI1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 76-295
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Séquence
- LLEAASYLEQ IEKENKKCEH GYASSFPSMP SPRLQHSKPP RRLSRAQKHS SGSSNTSTAN RSTHNELEKN RRAHLRLCLE RLKVLIPLGP DCTRHTTLGL LNKAKAHIKK LEEAERKSQH QLENLEREQR FLKWRLEQLQ GPQEMERIRM DSIGSTISSD RSDSEREEIE VDVESTEFSH GEVDNISTTS ISDIDDHSSL PSIGSDEGYS SASVKLSFTS
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 76-295 of human MXI1 (NP_569157.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- MXI1 (MAX Interactor 1 (MXI1))
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Autre désignation
- MXI1
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Sujet
- Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.,MXI1,MAD2,MXD2,MXI,bHLHc11,Epigenetics & Nuclear Signaling,Transcription Factors,MXI1
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Poids moléculaire
- 20 kDa/21 kDa/26 kDa/32 kDa
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ID gène
- 4601
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UniProt
- P50539
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Pathways
- Maintenance of Protein Location
Antigène
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