NLRC4 anticorps (AA 1-250)

N° du produit ABIN6144657

L’anticorps Lapin Polyclonal anti-NLRC4 a été validé pour WB et IF. Il convient pour détecter NLRC4 dans des échantillons de Humain.

Aperçu rapide pour NLRC4 anticorps (AA 1-250) (ABIN6144657)

Antigène: NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRC4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-NLRC4 anticorps

Épitope: AA 1-250

Séquence: MNFIKDNSRA LIQRMGMTVI KQITDDLFVW NVLNREEVNI ICCEKVEQDA ARGIIHMILK KGSESCNLFL KSLKEWNYPL FQDLNGQSLF HQTSEGDLDD LAQDLKDLYH TPSFLNFYPL GEDIDIIFNL KSTFTEPVLW RKDQHHHRVE QLTLNGLLQA LQSPCIIEGE SGKGKSTLLQ RIAMLWGSGK CKALTKFKFV FFLRLSRAQG GLFETLCDQL LDIPGTIRKQ TFMAMLLKLR QRVLFLLDGY

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human NLRC4 (NP_067032.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NLRC4

Antigène: NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

Autre désignation: NLRC4

Sujet: This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.,NLRC4,AIFEC,CARD12,CLAN,CLAN1,CLANA,CLANB,CLANC,CLAND,CLR2.1,FCAS4,IPAF,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Caspases,Cell Cycle,Endocrine & Metabolism,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,NLRC4

Poids moléculaire: 10 kDa/18 kDa/40 kDa/116 kDa

ID gène: 58484

UniProt: Q9NPP4

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome