PDE1A anticorps (AA 446-545)

N° du produit ABIN6145346

Cet anticorps anti-PDE1A est un anticorps Lapin Polyclonal détectant PDE1A dans WB. Adapté pour Humain.

Aperçu rapide pour PDE1A anticorps (AA 446-545) (ABIN6145346)

Antigène: PDE1A (Phosphodiesterase 1A (PDE1A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE1A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PDE1A anticorps

Épitope: AA 446-545

Séquence: EASKAETSSY VASSSTTIVG LHIADALRRS NTKGSMSDGS YSPDYSLAAV DLKSFKNNLV DIIQQNKERW KELAAQGESD LHKNSEDLVN AEEKHDETHS

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 446-545 of human PDE1A (NP_005010.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PDE1A

Antigène: PDE1A (Phosphodiesterase 1A (PDE1A))

Autre désignation: PDE1A

Sujet: Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1, MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109], Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM, Oct 2009],PDE1A,CAM-PDE-1A,HCAM-1,HCAM1,HSPDE1A,PDE1A

Poids moléculaire: 57 kDa/58 kDa/59 kDa/60 kDa/61 kDa/62 kDa/63 kDa

ID gène: 5136

UniProt: P54750

Pathways: Neurotrophin Signaling Pathway, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma