PHKG2 anticorps (AA 237-406)
Aperçu rapide pour PHKG2 anticorps (AA 237-406) (ABIN6145563)
Antigène
Voir toutes PHKG2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 237-406
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Séquence
- RQILMLRMIM EGQYQFSSPE WDDRSSTVKD LISRLLQVDP EARLTAEQAL QHPFFERCEG SQPWNLTPRQ RFRVAVWTVL AAGRVALSTH RVRPLTKNAL LRDPYALRSV RHLIDNCAFR LYGHWVKKGE QQNRAALFQH RPPGPFPIMG PEEEGDSAAI TEDEAVLVLG
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 237-406 of human PHKG2 (NP_000285.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- PHKG2 (phosphorylase Kinase, gamma 2 (Testis) (PHKG2))
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Autre désignation
- PHKG2
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Sujet
- Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9C, also known as autosomal liver glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.,PHKG2,GSD9C,Cancer,Signal Transduction,Kinase,Endocrine & Metabolism,Carbohydrate metabolism,PHKG2
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Poids moléculaire
- 43 kDa/46 kDa
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ID gène
- 5261
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UniProt
- P15735
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Pathways
- Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
Antigène
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