PIAS4 anticorps (AA 60-260)

N° du produit ABIN6145602

Cet anticorps anti-PIAS4 est un anticorps Lapin Polyclonal détectant PIAS4 dans WB. Adapté pour Humain.

Aperçu rapide pour PIAS4 anticorps (AA 60-260) (ABIN6145602)

Antigène: PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIAS4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PIAS4 anticorps

Épitope: AA 60-260

Séquence: ELYETRYAKK NSEPAPQPHR PLDPLTMHST YDRAGAVPRT PLAGPNIDYP VLYGKYLNGL GRLPAKTLKP EVRLVKLPFF NMLDELLKPT ELVPQNNEKL QESPCIFALT PRQVELIRNS RELQPGVKAV QVVLRICYSD TSCPQEDQYP PNIAVKVNHS YCSVPGYYPS NKPGVEPKRP CRPINLTHLM YLSSATNRIT V

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 60-260 of human PIAS4 (NP_056981.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PIAS4

Antigène: PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))

Autre désignation: PIAS4

Sujet: Functions as an E3-type small ubiquitin-like modifier (SUMO ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Mediates sumoylation of CEBPA, PARK7, HERC2, MYB, TCF4 and RNF168. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation.,PIAS4,PIAS-gamma,PIASY,Piasg,ZMIZ6,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,NF-kB Signaling Pathway,PIAS4

Poids moléculaire: 56 kDa

ID gène: 51588

UniProt: Q8N2W9

Pathways: Signalistation JAK/STAT, Interferon-gamma Pathway, Positive Regulation of Response to DNA Damage Stimulus