PLOD2 anticorps (AA 470-650)

N° du produit ABIN6145788

Détail du produit anti-PLOD2 anticorps

Antigène: PLOD2 (Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2))

Épitope: AA 470-650

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLOD2 est non-conjugé

Application: Western Blotting (WB)

Séquence: KTLRSEMNER NYFVRDKLDP DMALCRNARE MTLQREKDSP TPETFQMLSP PKGVFMYISN RHEFGRLLST ANYNTSHYNN DLWQIFENPV DWKEKYINRD YSKIFTENIV EQPCPDVFWF PIFSEKACDE LVEEMEHYGK WSGGKHHDSR ISGGYENVPT DDIHMKQVDL ENVWLHFIRE F

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 470-650 of human PLOD2 (NP_891988.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PLOD2

Antigène: PLOD2 (Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2))

Autre désignation: PLOD2 (PLOD2 Produits)

Synonymes: anticorps D530025C14Rik, anticorps LH2, anticorps Plod-2, anticorps TLH, anticorps procollagen lysine, 2-oxoglutarate 5-dioxygenase 2, anticorps procollagen-lysine,2-oxoglutarate 5-dioxygenase 2, anticorps Plod2, anticorps PLOD2

Sujet: The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.,PLOD2,BRKS2,LH2,TLH,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Collagen,Endocrine & Metabolism,PLOD2

Poids moléculaire: 49 kDa/84 kDa/87 kDa

ID gène: 5352

UniProt: O00469

Pathways: SARS-CoV-2 Protein Interactome