PPL anticorps (AA 1-130)

N° du produit ABIN6146036

Cet anticorps Lapin Polyclonal détecte spécifiquement PPL dans WB et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour PPL anticorps (AA 1-130) (ABIN6146036)

Antigène: PPL (Periplakin (PPL))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPL est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-PPL anticorps

Épitope: AA 1-130

Séquence: MNSLFRKRNK GKYSPTVQTR SISNKELSEL IEQLQKNADQ VEKNIVDTEA KMQSDLARLQ EGRQPEHRDV TLQKVLDSEK LLYVLEADAA IAKHMKHPQG DMIAEDIRQL KERVTNLRGK HKQIYRLAVK

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human PPL (NP_002696.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PPL

Antigène: PPL (Periplakin (PPL))

Autre désignation: PPL

Sujet: The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.,PPL,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Immunology & Inflammation,PPL

Poids moléculaire: 204 kDa

ID gène: 5493

UniProt: O60437