RAD23B anticorps (AA 50-150)

N° du produit ABIN6146632

L’anticorps Lapin Polyclonal anti-RAD23B a été validé pour WB, IHC et IF. Il convient pour détecter RAD23B dans des échantillons de Humain.

Aperçu rapide pour RAD23B anticorps (AA 50-150) (ABIN6146632)

Antigène: RAD23B (RAD23 Homolog B (RAD23B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD23B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-RAD23B anticorps

Épitope: AA 50-150

Séquence: GKILNDDTAL KEYKIDEKNF VVVMVTKPKA VSTPAPATTQ QSAPASTTAV TSSTTTTVAQ APTPVPALAP TSTPASITPA SATASSEPAP ASAAKQEKPA E

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Rad23B (NP_002865.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RAD23B

Antigène: RAD23B (RAD23 Homolog B (RAD23B))

Autre désignation: RAD23B

Sujet: The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,RAD23B,HHR23B,HR23B,P58,Epigenetics & Nuclear Signaling,DNA Damage & Repair,RAD23B

Poids moléculaire: 35 kDa/43 kDa

ID gène: 5887

UniProt: P54727

Pathways: Réparation de l'ADN