RIPK3 anticorps (AA 1-120)

N° du produit ABIN6146964

Cet anticorps Lapin Polyclonal détecte spécifiquement RIPK3 dans WB, IHC et IF. Il présente une réactivité envers Humain et a été mentionné dans 3+ publications.

Aperçu rapide pour RIPK3 anticorps (AA 1-120) (ABIN6146964)

Antigène: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RIPK3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-RIPK3 anticorps

Épitope: AA 1-120

Séquence: MSCVKLWPSG APAPLVSIEE LENQELVGKG GFGTVFRAQH RKWGYDVAVK IVNSKAISRE VKAMASLDNE FVLRLEGVIE KVNWDQDPKP ALVTKFMENG SLSGLLQSQC PRPWPLLCRL

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human RIPK3 (NP_006862.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-RIPK3 (ABIN6146964)

Qin, Yang, Huang, Du, Mai, Xiao, Lü: "Sulforaphane attenuates microglia-mediated neuronal necroptosis through down-regulation of MAPK/NF-κB signaling pathways in LPS-activated BV-2 microglia." dans: Pharmacological research, Vol. 133, pp. 218-235, (2018) (PubMed).

Mengying, Yiyue, Tong, Yue, Limpanont, Ping, Okanurak, Yanqi, Dekumyoy, Hongli, Watthanakulpanich, Zhongdao, Zhi, Zhiyue: "Apoptosis and necroptosis of mouse hippocampal and parenchymal astrocytes, microglia and neurons caused by Angiostrongylus cantonensis infection." dans: Parasites & vectors, Vol. 10, Issue 1, pp. 611, (2018) (PubMed).

Huang, Zheng, Wang, Chen, He, Zhang, Xu, Zhao, Shi, Wang, Zhu, Han: "The MLKL Channel in Necroptosis Is an Octamer Formed by Tetramers in a Dyadic Process." dans: Molecular and cellular biology, Vol. 37, Issue 5, (2017) (PubMed).

Détails sur RIPK3

Antigène: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Autre désignation: RIPK3

Sujet: The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.,RIPK3,RIP3,Signal Transduction,Kinase,Serine/threonine kinases,MAPK-JNK Signaling Pathway,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,RIPK3

Poids moléculaire: 25 kDa/27 kDa/56 kDa

ID gène: 11035

UniProt: Q9Y572

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades