RORA anticorps (AA 169-468)
Aperçu rapide pour RORA anticorps (AA 169-468) (ABIN6147077)
Antigène
Voir toutes RORA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 169-468
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Séquence
- DIQPSPDQSG LDINGIKPEP ICDYTPASGF FPYCSFTNGE TSPTVSMAEL EHLAQNISKS HLETCQYLRE ELQQITWQTF LQEEIENYQN KQREVMWQLC AIKITEAIQY VVEFAKRIDG FMELCQNDQI VLLKAGSLEV VFIRMCRAFD SQNNTVYFDG KYASPDVFKS LGCEDFISFV FEFGKSLCSM HLTEDEIALF SAFVLMSADR SWLQEKVKIE KLQQKIQLAL QHVLQKNHRE DGILTKLICK VSTLRALCGR HTEKLMAFKA IYPDIVRLHF PPLYKELFTS EFEPAMQIDG
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 169-468 of human RORA (NP_599024.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- RORA (RAR-Related Orphan Receptor A (RORA))
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Autre désignation
- RORA
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Sujet
- The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene.,RORA,NR1F1,ROR1,ROR2,ROR3,RZR-ALPHA,RZRA,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Nuclear hormone receptors,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Neuroscience,RORA
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Poids moléculaire
- 53 kDa/58 kDa/61 kDa/63 kDa
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ID gène
- 6095
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UniProt
- P35398
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Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
Antigène
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