Rubicon anticorps (AA 1-200)
Aperçu rapide pour Rubicon anticorps (AA 1-200) (ABIN6147300)
Antigène
Voir toutes Rubicon (KIAA0226) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-200
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Séquence
- MRPEGAGMEL GGGEERLPEE SRREHWQLLG NLKTTVEGLV STNSPNVWSK YGGLERLCRD MQSILYHGLI RDQACRRQTD YWQFVKDIRW LSPHSALHVE KFISVHENDQ SSADGASERA VAELWLQHSL QYHCLSAQLR PLLGDRQYIR KFYTDAAFLL SDAHVTAMLQ CLEAVEQNNP RLLAQIDASM FARKHESPLL
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Réactivité croisée
- Souris
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human Rubicon (NP_055502.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Rubicon (KIAA0226) (KIAA0226)
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Autre désignation
- RUBCN
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Sujet
- The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,RUBCN,KIAA0226,RUBICON,SCAR15,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Cardiovascular,Heart,RUBCN
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Poids moléculaire
- 102 kDa/103 kDa/108 kDa
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ID gène
- 9711
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UniProt
- Q92622
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Pathways
- Autophagy
Antigène
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