SESN3 anticorps (AA 1-310)
Aperçu rapide pour SESN3 anticorps (AA 1-310) (ABIN6147627)
Antigène
Voir toutes SESN3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-310
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Séquence
- MNRGGGSPSA AANYLLCTNC RKVLRKDKRI RVSQPLTRGP SAFIPEKEVV QANTVDERTN FLVEEYSTSG RLDNITQVMS LHTQYLESFL RSQFYMLRMD GPLPLPYRHY IAIMAAARHQ CSYLINMHVD EFLKTGGIAE WLNGLEYVPQ RLKNLNEINK LLAHRPWLIT KEHIQKLVKT GENNWSLPEL VHAVVLLAHY HALASFVFGS GINPERDPEI SNGFRLISVN NFCVCDLAND NNIENASLSG SNFGIVDSLS ELEALMERMK RLQEEREDEE ASQEEMSTRF EKEKKESLFV VSGDTFHSFP
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Réactivité croisée
- Humain
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human SESN3 (NP_653266.2).
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Isotype
- IgG
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Indications d'application
- WB,1:200 - 1:2000
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- SESN3 (Sestrin 3 (SESN3))
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Autre désignation
- SESN3
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Sujet
- This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.,SESN3,SEST3,sestrin-3,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Endocrine & Metabolism,AMPK Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Cardiovascular,Hypoxia,Hypoxia-Regulated,SESN3
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Poids moléculaire
- 36 kDa/41 kDa/57 kDa
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ID gène
- 143686
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UniProt
- P58005
Antigène
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