SET/TAF-I anticorps (AA 146-277)

N° du produit ABIN6147629

Cet anticorps anti-SET/TAF-I est un anticorps Lapin Polyclonal détectant SET/TAF-I dans WB, IHC et IF. Adapté pour Humain.

Aperçu rapide pour SET/TAF-I anticorps (AA 146-277) (ABIN6147629)

Antigène: SET/TAF-I (SET) (SET Nuclear Oncogene (SET))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SET/TAF-I est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-SET/TAF-I anticorps

Épitope: AA 146-277

Séquence: NESGDPSSKS TEIKWKSGKD LTKRSSQTQN KASRKRQHEE PESFFTWFTD HSDAGADELG EVIKDDIWPN PLQYYLVPDM DDEEGEGEED DDDDEEEEGL EDIDEEGDED EGEEDEDDDE GEEGEEDEGE DD

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 146-277 of human SET/TAF1 (NP_003002.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SET/TAF-I

Antigène: SET/TAF-I (SET) (SET Nuclear Oncogene (SET))

Autre désignation: SET

Sujet: The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene.,SET,2PP2A,I2PP2A,IGAAD,IPP2A2,PHAPII,TAF-I,TAF-IBETA,Epigenetics & Nuclear Signaling,Chromatin Remodeling,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Immunology & Inflammation,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,SET

Poids moléculaire: 30 kDa/31 kDa/32 kDa/33 kDa

ID gène: 6418

UniProt: Q01105

Pathways: Apoptose