HDAC4 anticorps

N° du produit ABIN6147718

L’anticorps anti-HDAC4 Monoclonal Lapin est utilisé pour la détection de HDAC4 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour HDAC4 anticorps (ABIN6147718)

Antigène: HDAC4 (Histone Deacetylase 4 (HDAC4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp HDAC4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HDAC4 anticorps

Réactivité croisée: Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human HDAC4

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur HDAC4

Antigène: HDAC4 (Histone Deacetylase 4 (HDAC4))

Autre désignation: HDAC4

Sujet: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008],AHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA,Cardiovascular,Cell Biology & Developmental Biology,Cell Cycle,Epigenetics & Nuclear Signaling,G1/S Checkpoint,Heart,Heart_Hypertrophy,Immunology & Inflammation,NF-kB Signaling Pathway,Notch Signaling Pathway,Nuclear Receptor Signaling,Signal Transduction,Stem Cells,Wnt/β-Catenin Signaling Pathway,HDAC4

Poids moléculaire: 140 kDa

ID gène: 9759

UniProt: P56524

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process