SIGLEC8 anticorps (AA 17-363)
Aperçu rapide pour SIGLEC8 anticorps (AA 17-363) (ABIN6147766)
Antigène
Voir toutes SIGLEC8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 17-363
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Séquence
- MEGDRQYGDG YLLQVQELVT VQEGLCVHVP CSFSYPQDGW TDSDPVHGYW FRAGDRPYQD APVATNNPDR EVQAETQGRF QLLGDIWSND CSLSIRDARK RDKGSYFFRL ERGSMKWSYK SQLNYKTKQL SVFVTALTHR PDILILGTLE SGHSRNLTCS VPWACKQGTP PMISWIGASV SSPGPTTARS SVLTLTPKPQ DHGTSLTCQV TLPGTGVTTT STVRLDVSYP PWNLTMTVFQ GDATASTALG NGSSLSVLEG QSLRLVCAVN SNPPARLSWT RGSLTLCPSR SSNPGLLELP RVHVRDEGEF TCRAQNAQGS QHISLSLSLQ NEGTGTSRPV SQVTLAA
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 17-363 of human Siglec-8 (NP_055257.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
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Autre désignation
- SIGLEC8
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Sujet
- Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM, MIM 603492) that mediates an association with SLAM-associated protein (SAP, MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010],SIGLEC8,SAF2,SIGLEC-8,SIGLEC8L,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Cytoskeleton,Immunology & Inflammation,CD markers,SIGLEC8
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Poids moléculaire
- 44 kDa/46 kDa/54 kDa
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ID gène
- 27181
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UniProt
- Q9NYZ4
Antigène
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