SIRT6 anticorps (C-Term)

N° du produit ABIN6147800

Cet anticorps anti-SIRT6 est un anticorps Lapin Polyclonal détectant SIRT6 dans WB. Adapté pour Souris. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour SIRT6 anticorps (C-Term) (ABIN6147800)

Antigène: SIRT6 (Sirtuin 6 (SIRT6))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRT6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SIRT6 anticorps

Épitope: C-Term

Séquence: NLQPTKHDRQ ADLRIHGYVD EVMCRLMKHL GLEIPAWDGP CVLDKALPPL PRPVALKAEP PVHLNGAVHV SYKSKPNSPI LHRPPKRVKT EAAPS

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of mouse SIRT6 (NP_001156902.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-SIRT6 (ABIN6147800)

Zhu, Yan, Shao, Tian, Zhou: "Downregulation of SIRT6 is associated with poor prognosis in patients with non-small cell lung cancer." dans: The Journal of international medical research, Vol. 46, Issue 4, pp. 1517-1527, (2018) (PubMed).

Détails sur SIRT6

Antigène: SIRT6 (Sirtuin 6 (SIRT6))

Autre désignation: SIRT6

Sujet: This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.,SIRT6,SIR2L6,sirtuin 6,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Deacetylation,SIRT6

Poids moléculaire: 36 kDa/39 kDa

ID gène: 50721

UniProt: Q8N6T7