SKIL anticorps (AA 420-684)

N° du produit ABIN6147811

Cet anticorps anti-SKIL est un anticorps Lapin Polyclonal détectant SKIL dans WB. Adapté pour Humain.

Aperçu rapide pour SKIL anticorps (AA 420-684) (ABIN6147811)

Antigène: SKIL (SKI-Like Oncogene (SKIL))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SKIL est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SKIL anticorps

Épitope: AA 420-684

Séquence: SQSKELTKTE ASKSISRQSE KAHSSGKLQK TVSYPDVSLE EQEKMDLKTS RELCSRLDAS ISNNSTSKRK SESATCNLVR DINKVGIGLV AAASSPLLVK DVICEDDKGK IMEEVMRTYL KQQEKLNLIL QKKQQLQMEV KMLSSSKSMK ELTEEQQNLQ KELESLQNEH AQRMEEFYVE QKDLEKKLEQ IMKQKCTCDS NLEKDKEAEY AGQLAELRQR LDHAEADRQE LQDELRQERE ARQKLEMMIK ELKLQILKSS KTAKE

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 420-684 of human SKIL (NP_001234937.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SKIL

Antigène: SKIL (SKI-Like Oncogene (SKIL))

Autre désignation: SKIL

Sujet: The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.,SKIL,SNO,SnoA,SnoI,SnoN,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Target gene,SKIL

Poids moléculaire: 44 kDa/46 kDa/71 kDa/74 kDa/76 kDa

ID gène: 6498

UniProt: P12757

Pathways: Positive Regulation of Response to DNA Damage Stimulus