CD34 anticorps
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- Antigène Voir toutes CD34 Anticorps
- CD34
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Reactivité
- Humain, Primate
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD34 est non-conjugé
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Application
- Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- Specificité
- This antibody reacts with Class II epitope on CD34 (Mucosialin), a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells, it is gradually lost on progenitor cells. This antibody has been also used as an endothelial marker.
- Réactivité croisée (Details)
- Species reactivity (tested):Human, Non-Human Primates, negative on Rat, Bovine, Sheep, Canine (Dog)
- Purification
- Protein-A affinity chromatography
- Pureté
- > 95 % pure by SDS-PAGE
- Immunogène
- Human endothelial vesicles
- Clone
- QBEnd-10
- Isotype
- IgG1
- Top Product
- Discover our top product CD34 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Azide free phosphate buffered saline (PBS), approx. pH 7.4, 0.2 μm filter sterilized
- Agent conservateur
- Azide free
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Antigène
- CD34
- Autre désignation
- CD34 (CD34 Produits)
- Synonymes
- anticorps AU040960, anticorps CD34 molecule, anticorps CD34 antigen, anticorps CD34, anticorps Cd34
- Sujet
- CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.Synonyms: Hematopoietic progenitor cell antigen CD34, Hematopoietic progenitor cell marker
- ID gène
- 947
- NCBI Accession
- NP_001020280
- UniProt
- P28906
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