CD34 anticorps (PE)

N° du produit ABIN614814

Cet anticorps anti-CD34 est un anticorps Souris Monoclonal détectant CD34 dans FACS. Adapté pour Humain et Primate.

Aperçu rapide pour CD34 anticorps (PE) (ABIN614814)

Antigène: CD34

Reactivité: Humain, Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD34 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: QBEnd-10

Détail du produit anti-CD34 anticorps (PE)

Specificité: This antibody reacts with Class II epitope on CD34 (Mucosialin), a 110-115 kDa monomeric transmembrane phosphoglycoprotein expressed on hematopoietic progenitors cells and on the most pluripotential stem cells, it is gradually lost on progenitor cells. This antibody has been also used as an endothelial marker.

Réactivité croisée (Details): Species reactivity (tested):Human, Non-Human Primates, negative on Rat, Bovine, Sheep, Canine (Dog)

Immunogène: Human endothelial vesicles

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE! This product is photosensitive and should be protected from light.

Stock: 4 °C

Détails sur CD34

Antigène: CD34

Autre désignation: CD34

Sujet: CD34 is a highly glycosylated monomeric 111-115 kDa surface protein, which is present on many stem cell populations. It is a well established stem cell marker, though its expression on human hematopoietic stem cells is reversible. CD34 probably serves as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions.Synonyms: Hematopoietic progenitor cell antigen CD34, Hematopoietic progenitor cell marker

ID gène: 947

NCBI Accession: NP_001020280

UniProt: P28906