Ubinuclein 1 anticorps (N-Term)

N° du produit ABIN614815

Cet anticorps Souris Monoclonal détecte spécifiquement Ubinuclein 1 dans WB et IP. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Ubinuclein 1 anticorps (N-Term) (ABIN614815)

Antigène: Ubinuclein 1 (UBN1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Ubinuclein 1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: UBN1-02

Détail du produit anti-Ubinuclein 1 anticorps

Épitope: AA 1-190, N-Term

Specificité: This antibody recognizes N-terminal part of ubinuclein 1 (UBN1), a widely expressed nuclear and adhesion complex protein. Western blotting analysis reveals UBN1 as a 165 kDa band.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Protein-A affinity chromatography

Pureté: > 95 % pure by SDS-PAGE

Immunogène: Recombinant protein corresponding to amino acids 1-190 of ubinuclein 1

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur Ubinuclein 1

Antigène: Ubinuclein 1 (UBN1)

Autre désignation: Ubinuclein-1 (UBN1)

Sujet: Ubinuclein 1 (UBN1) is a ubiquitously expressed evolutionarily conserved protein which binds to proliferation-promoting genes that are repressed by formation of senescence-associated heterochromatin foci (SAHF). Ubinuclein 1 associates with various transcription factors and with histone methyltransferase activity, is indispensable for SAHF formation and appears to be a regulator of senescence. Although in most cells ubinuclein is localized to the nucleus, in cells forming tight junctions it is recruited to the cell adhesion complexes, dependently on the cell density.Synonyms: HIRA-binding protein, Protein VT4, Ubiquitously expressed nuclear protein

ID gène: 29855

NCBI Accession: NP_058632

UniProt: Q9NPG3