SPAG8 anticorps (AA 220-420)

N° du produit ABIN6148323

Détail du produit anti-SPAG8 anticorps

Antigène: SPAG8 (Sperm Associated Antigen 8 (SPAG8))

Épitope: AA 220-420

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPAG8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: LVADRVPNYT SWSQHCPWEP QKQPPWEFLQ VLEPGARGLW KPPDIKGKLM VCYETLPRGQ CLLYNWEEER ATNHLDQVPS MQDGSESFFF RHGHRGLLTM QLKSPMPSST TQKDSYQPPG NVYWPLRGKR EAMLEMLLQH QICKEVQAEQ EPTRKLFEVE SVTHHDYRME LAQAGTPAPT KPHDYRQEQP ETFWIQRAPQ L

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 220-420 of human SPAG8 (NP_758516.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SPAG8

Antigène: SPAG8 (Sperm Associated Antigen 8 (SPAG8))

Autre désignation: SPAG8 (SPAG8 Produits)

Synonymes: anticorps BS-84, anticorps HSD-1, anticorps SMP1, anticorps SPAG3, anticorps hSMP-1, anticorps MH-SPAG8, anticorps sperm associated antigen 8, anticorps SPAG8, anticorps Spag8

Sujet: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. This protein interacts with ACT (activator of CREM in testis) and may play a role in CREM (cAMP response element modulator)-ACT-mediated gene transcription during spermatogenesis. This protein may also play a role in spermatogenesis by regulating microtubule formation and cell division. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.,SPAG8,BS-84,CILD28,CT142,HSD-1,SMP1,SPAG3,hSMP-1,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Stem Cells,Germline Stem Cells,SPAG8

Poids moléculaire: 44 kDa/51 kDa/53 kDa

ID gène: 26206

UniProt: Q99932