STK36 anticorps (AA 250-450)
Aperçu rapide pour STK36 anticorps (AA 250-450) (ABIN6148614)
Antigène
Voir toutes STK36 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 250-450
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 250-450 of human STK36 (NP_056505.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- STK36 (serine/threonine Kinase 36 (STK36))
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Autre désignation
- STK36
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Sujet
- This gene encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that this gene is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants.,STK36,FU,Cancer,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,STK36
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Poids moléculaire
- 141 kDa/143 kDa
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ID gène
- 27148
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UniProt
- Q9NRP7
Antigène
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