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STK36 anticorps (Internal Region)

STK36 Reactivité: Humain, Souris, Rat ELISA, WB, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6259306
  • Antigène Voir toutes STK36 Anticorps
    STK36 (serine/threonine Kinase 36 (STK36))
    Épitope
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 17
    • 2
    • 1
    Lapin
    Clonalité
    • 20
    Polyclonal
    Conjugué
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp STK36 est non-conjugé
    Application
    • 12
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    STK36 Antibody detects endogenous levels of total STK36.
    Homologie
    Pig,Bovine,Horse,Sheep,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human STK36, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product STK36 Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    STK36 (serine/threonine Kinase 36 (STK36))
    Autre désignation
    STK36 (STK36 Produits)
    Synonymes
    anticorps FU, anticorps fused-like, anticorps 1700112N14Rik, anticorps B930045J24, anticorps Fused, anticorps mKIAA1278, anticorps fu, anticorps si:dkey-180i4.3, anticorps zgc:152944, anticorps serine/threonine kinase 36, anticorps serine/threonine kinase 36 (fused homolog, Drosophila), anticorps STK36, anticorps Stk36, anticorps stk36
    Sujet

    Description: Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors (PubMed:10806483). Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization (PubMed:10806483). GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur (PubMed:10806483). Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function (By similarity). Essential for construction of the central pair apparatus of motile cilia.

    Gene: STK36

    Poids moléculaire
    170 kDa
    ID gène
    27148
    UniProt
    Q9NRP7
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