STK4 anticorps (AA 303-487)
Aperçu rapide pour STK4 anticorps (AA 303-487) (ABIN6148620)
Antigène
Voir toutes STK4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 303-487
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Séquence
- KRQESQQREV DQDDEENSEE DEMDSGTMVR AVGDEMGTVR VASTMTDGAN TMIEHDDTLP SQLGTMVINA EDEEEEGTMK RRDETMQPAK PSFLEYFEQK EKENQINSFG KSVPGPLKNS SDWKIPQDGD YEFLKSWTVE DLQKRLLALD PMMEQEIEEI RQKYQSKRQP ILDAIEAKKR RQQNF
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 303-487 of human MST1/STK4 (NP_006273.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Protein kinase A inhibitor, H89, enhances survival and clonogenicity of dissociated human embryonic stem cells through Rho-associated coiled-coil containing protein kinase (ROCK) inhibition." dans: Human reproduction (Oxford, England), Vol. 31, Issue 4, pp. 832-43, (2016) (PubMed).
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: "Protein kinase A inhibitor, H89, enhances survival and clonogenicity of dissociated human embryonic stem cells through Rho-associated coiled-coil containing protein kinase (ROCK) inhibition." dans: Human reproduction (Oxford, England), Vol. 31, Issue 4, pp. 832-43, (2016) (PubMed).
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- STK4 (serine/threonine Kinase 4 (STK4))
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Autre désignation
- STK4
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Sujet
- The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.,KRS2,MST1,YSK3,STK4,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Hippo Signaling Pathway,Cardiovascular,Heart,Hypertrophy,STK4
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Poids moléculaire
- 52 kDa/55 kDa
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ID gène
- 6789
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UniProt
- Q13043
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Pathways
- Tube Formation
Antigène
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