TET2 anticorps (AA 1833-2002)

N° du produit ABIN6149017

L’anticorps Lapin Polyclonal anti-TET2 a été validé pour WB, IHC et IF. Il convient pour détecter TET2 dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour TET2 anticorps (AA 1833-2002) (ABIN6149017)

Antigène: TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TET2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-TET2 anticorps

Épitope: AA 1833-2002

Séquence: VQGVASGAED NDEVWSDSEQ SFLDPDIGGV AVAPTHGSIL IECAKRELHA TTPLKNPNRN HPTRISLVFY QHKSMNEPKH GLALWEAKMA EKAREKEEEC EKYGPDYVPQ KSHGKKVKRE PAEPHETSEP TYLRFIKSLA ERTMSVTTDS TVTTSPYAFT RVTGPYNRYI

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1833-2002 of human TET2 (NP_001120680.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-TET2 (ABIN6149017)

Yu, Liu, Liu, Wang, Liu, Miao, Du, Yang: "Ascorbic acid induces global epigenetic reprogramming to promote meiotic maturation and developmental competence of porcine oocytes." dans: Scientific reports, Vol. 8, Issue 1, pp. 6132, (2018) (PubMed).

Détails sur TET2

Antigène: TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))

Autre désignation: TET2

Sujet: The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene.,MDS,KIAA1546,TET2,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,DNA Demethylation,TET2

Poids moléculaire: 130 kDa/133 kDa/223 kDa

ID gène: 54790

UniProt: Q6N021

Pathways: L'effet Warburg